Visfatin/Nampt induces telomere damage and senescence in human endothelial cells
journal contribution
posted on 2022-03-29, 13:22 authored by Laura A. Villalobos, Anna Uryga, Tania Romacho, Alejandra Leivas, Carlos F. Sánchez-Ferrer, Jorge D. Erusalimsky, Concepción PeiróThe adipose tissue is an active endocrine organ that releases a wide array of substances, globally termed adipokines. Among these, visfatin is a multifaceted molecule, structurally identical to the extracellular form of nicotinamide phosphoribosyltransferase (Nampt), which enzymatically converts nicotinamide into nicotinamide mononucleotide (NMN) and whose circulating levels are enhanced in metabolic disorders
History
Published in
International Journal of CardiologyPublisher
ElsevierVersion
- VoR (Version of Record)
Citation
Villalobos, L.A., Uryga, A., Romacho, T., Leivas, A., Sánchez-Ferrer, C.F., Erusalimsky, J.D. and Peiró, C. (2014) 'Visfatin/Nampt induces telomere damage and senescence in human endothelial cells', International Journal of Cardiology, 175(3), pp.573-575Print ISSN
0167-5273Cardiff Met Affiliation
- Cardiff School of Sport and Health Sciences
Cardiff Met Authors
Jorge D. ErusalimskyCardiff Met Research Centre/Group
- Cellular Senescence and Pathophysiology
Copyright Holder
- © The Authors
Language
- en
