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Visfatin/Nampt induces telomere damage and senescence in human endothelial cells

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journal contribution
posted on 2022-03-29, 13:22 authored by Laura A. Villalobos, Anna Uryga, Tania Romacho, Alejandra Leivas, Carlos F. Sánchez-Ferrer, Jorge D. Erusalimsky, Concepción Peiró
The adipose tissue is an active endocrine organ that releases a wide array of substances, globally termed adipokines. Among these, visfatin is a multifaceted molecule, structurally identical to the extracellular form of nicotinamide phosphoribosyltransferase (Nampt), which enzymatically converts nicotinamide into nicotinamide mononucleotide (NMN) and whose circulating levels are enhanced in metabolic disorders


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International Journal of Cardiology




  • VoR (Version of Record)


Villalobos, L.A., Uryga, A., Romacho, T., Leivas, A., Sánchez-Ferrer, C.F., Erusalimsky, J.D. and Peiró, C. (2014) 'Visfatin/Nampt induces telomere damage and senescence in human endothelial cells', International Journal of Cardiology, 175(3), pp.573-575

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Cardiff Met Affiliation

  • Cardiff School of Sport and Health Sciences

Cardiff Met Authors

Jorge D. Erusalimsky

Cardiff Met Research Centre/Group

  • Cellular Senescence and Pathophysiology

Copyright Holder

  • © The Authors


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