Visfatin/Nampt induces telomere damage and senescence in human endothelial cells

A. Villalobos, Laura; Uryga, Anna; Romacho, Tania; Leivas, Alejandra; F. Sánchez-Ferrer, Carlos; Erusalimsky, Jorge D.; Peiró, Concepción

PIIS0167527314010110.pdf (528.6 kB)

Visfatin/Nampt induces telomere damage and senescence in human endothelial cells

journal contribution

posted on 2022-03-29, 13:22 authored by Laura A. Villalobos, Anna Uryga, Tania Romacho, Alejandra Leivas, Carlos F. Sánchez-Ferrer, Jorge D. Erusalimsky, Concepción Peiró

The adipose tissue is an active endocrine organ that releases a wide array of substances, globally termed adipokines. Among these, visfatin is a multifaceted molecule, structurally identical to the extracellular form of nicotinamide phosphoribosyltransferase (Nampt), which enzymatically converts nicotinamide into nicotinamide mononucleotide (NMN) and whose circulating levels are enhanced in metabolic disorders

History

DOI

http://dx.doi.org/10.1016/j.ijcard.2014.05.028

Published in

International Journal of Cardiology

Publisher

Elsevier

Version

VoR (Version of Record)

Citation

Villalobos, L.A., Uryga, A., Romacho, T., Leivas, A., Sánchez-Ferrer, C.F., Erusalimsky, J.D. and Peiró, C. (2014) 'Visfatin/Nampt induces telomere damage and senescence in human endothelial cells', International Journal of Cardiology, 175(3), pp.573-575