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Visfatin/Nampt induces telomere damage and senescence in human endothelial cells

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journal contribution
posted on 29.03.2022, 13:22 by Laura A. Villalobos, Anna Uryga, Tania Romacho, Alejandra Leivas, Carlos F. Sánchez-Ferrer, Jorge D. Erusalimsky, Concepción Peiró
The adipose tissue is an active endocrine organ that releases a wide array of substances, globally termed adipokines. Among these, visfatin is a multifaceted molecule, structurally identical to the extracellular form of nicotinamide phosphoribosyltransferase (Nampt), which enzymatically converts nicotinamide into nicotinamide mononucleotide (NMN) and whose circulating levels are enhanced in metabolic disorders

History

Published in

International Journal of Cardiology

Publisher

Elsevier

Version

VoR (Version of Record)

Citation

Villalobos, L.A., Uryga, A., Romacho, T., Leivas, A., Sánchez-Ferrer, C.F., Erusalimsky, J.D. and Peiró, C. (2014) 'Visfatin/Nampt induces telomere damage and senescence in human endothelial cells', International Journal of Cardiology, 175(3), pp.573-575

Print ISSN

0167-5273

Cardiff Met Affiliation

  • Cardiff School of Sport and Health Sciences

Cardiff Met Authors

Jorge D. Erusalimsky

Cardiff Met Research Centre/Group

  • Cellular Senescence and Pathophysiology

Copyright Holder

© The Authors

Language

en