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Chemical characterisation and the anti-inflammatory, anti-angiogenic and antibacterial properties of date fruit (Phoenix dactylifera L.)

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journal contribution
posted on 2023-01-20, 10:59 authored by Hajer Taleb, Sarah Maddocks, Keith Morris, Ara Kanekanian


Ethnopharmacological relevance

Date fruit, Phoenix dactylifera L. has traditionally been used as a medicine in many cultures for the treatment of a range of ailments such as stomach and intestinal disorders, fever, oedema, bronchitis and wound healing.

Aim of the review

The present review aims to summarise the traditional use and application of P. dactylifera date fruit in different ethnomedical systems, additionally the botany and phytochemistry are identified. Critical evaluation of in vitro and in vitro studies examining date fruit in relation to anti-inflammatory, anti-angiogenic and antimicrobial activities are outlined.

Key findings

The ethnomedical use of P. dactylifera in the treatment of inflammatory disease has been previously identified and reported. Furthermore, date fruit and date fruit co-products such as date syrup are rich sources of polyphenols, anthocyanins, sterols and carotenoids. In vitro studies have demonstrated that date fruit exhibits antibacterial, anti-inflammatory and anti-angiogenic activity. The recent interest in the identification of the numerous health benefits of dates using in vitro and in vivo studies have confirmed that date fruit and date syrup have beneficial health effects that can be attributed to the presence of natural bioactive compounds.


Date fruit and date syrup have therapeutic properties, which have the potential to be beneficial to health. However, more investigations are needed to quantify and validate these effects.


Published in

Journal of Ethnopharmacology




  • AM (Accepted Manuscript)


Taleb, H., Maddocks, S. E., Morris, R. K., & Kanekanian, A. D. (2016) 'Chemical characterisation and the anti-inflammatory, anti-angiogenic and antibacterial properties of date fruit (Phoenix dactylifera L.)', Journal of Ethnopharmacology, 194, 457-468. DOI: 10.1016/j.jep.2016.10.032

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Cardiff Met Affiliation

  • Cardiff School of Sport and Health Sciences

Cardiff Met Authors

Sarah Maddocks Keith Morris

Cardiff Met Research Centre/Group

  • Microbiology & Infection

Copyright Holder

  • © The Publisher


  • en

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