76 - Alterations in Cardiac Mechanics following Ultra-endurance Exercise- Lord, R.pdf (470.78 kB)
Download file

Alterations in cardiac mechanics following ultra-endurance exercise: Insights from left and right ventricular area-deformation loops

Download (470.78 kB)
journal contribution
posted on 2023-01-23, 16:56 authored by Rachel LordRachel Lord, Keith George, John Somauroo, Michael StembridgeMichael Stembridge, Nikhil Jain, Martin D. Hoffman, Rob Shave, Francois Haddad, Euan Ashley, Helen Jones, David Oxborough

 

Background

The aim of this study was to use novel area-deformation (ε) loops to interrogate the interaction between the right ventricular (RV) and left ventricular (LV) mechanics following a 100-mile endurance run.

Methods

Fifteen participants (mean body mass, 70.1 ± 8.8 kg; mean age, 40 ± 8 years) were recruited for the study. Echocardiography was performed before the race, after the race, and 6 hours into recovery. RV and LV area and longitudinal ε were assessed using standard and speckle-tracking echocardiography. Following cubic spline interpolation, these variables were obtained across the same cardiac cycle and used to derive area-ε loops.

Results

The RV area-ε loop demonstrated a rightward shift after the race, with increased RV area (from 26.0 to 27.1 cm2) and reduced peak RV ε (from −28.6% to −25.8%). The recovery RV area-ε loop was similar to the postrace loop. A leftward shift was observed in the LV area-ε loop after the race, secondary to reduced LV area (from 35.8 to 32.5 cm2) and reduced peak ε (from −18.3% to −16.6%). In recovery, LV ε values returned toward baseline.

Conclusions

A 100-mile ultramarathon resulted in a rightward shift in the RV area-ε loop as a result of RV dilatation. There was a concomitant leftward shift in the LV area-ε loop as a result of underfilling of the left ventricle. At 6 hours after exercise, there was a partial recovery of the left ventricle, while RV function remained depressed. It appears that changes in RV function do not have a serial impact on the left ventricle during recovery from ultra-endurance activity.

History

Published in

Journal of the American Society of Echocardiography

Publisher

Elsevier

Version

AM (Accepted Manuscript)

Citation

Lord, R., George, K., Somauroo, J., Jain, N., Hoffman, M.D., Shave, R., Haddad, F., Ashley, E., Jones, H. and Oxborough, D. (2016) 'Alterations in cardiac mechanics following ultra-endurance exercise: Insights from left and right ventricular area-deformation loops', Journal of the American Society of Echocardiography, 29 (9), pp.879-887

Print ISSN

0894-7317

Cardiff Met Affiliation

  • Cardiff School of Sport and Health Sciences

Cardiff Met Authors

Rachel Lord Mike Stembridge

Cardiff Met Research Centre/Group

  • Cardiovascular Physiology

Copyright Holder

© The Publisher

Language

en